Dr. Kashif Rana
Dr. Kashif Rana is a highly accomplished molecular and cellular biologist specializing in pathology, virology, cell signaling, translational diagnostics, and drug discovery, with extensive experience in deciphering the complex regulatory mechanisms relevant to infectious and inflammatory diseases as well as cancer.
Bringing together a PhD in cell and molecular biology in France and a decade long research experience in Canada, Dr. Rana is highly proficient in applying advanced molecular biological and translational methodologies to drive strategic solutions. His core expertise lies in dissecting intracellular signal transduction cascades and leading assay development through the application of sophisticated molecular biological techniques.
Dr. Rana demonstrates strong project leadership, evidenced by his instrumental role in conceiving and directing large-scale, international research programs. This precise methodological focus directly translates to high-value consulting capabilities in diagnostics and R&D, offering clients deep expertise in strategic problem-solving and innovation.
Core Services
Drug Development and Repurposing
- Therapeutic Target Identification
- Screening and Drug Development
- Repurposing approved drugs for other modalities
Molecular Biology
- DNA/RNA extraction
- PCR and qPCR
- DNA sequencing (including Sanger and next-generation sequencing)
- Gene cloning and plasmid construction
- CRISPR gene editing
- siRNA/shRNA knockdown
- Gene expression analysis
- Protein expression and purification
- Protein-DNA interaction
Cell Biology
- Cell culture (primary cells, tumor cell lines)
- Plasmid transfection
- Generation of Stable Cell Lines
- Luminescence, fluorescence, UV-absorbance based cell assays
- Cell Imaging (IncuCyte, Immunofluorescence, Confocal)
Microbiology
- BSL-2/ BSL-3 containment labs
- Virus culture, detection and titration
- Lentivirus/ Retrovirus production and transduction
- Bacterial isolation and identification
Biomarker Discovery and Validation
- Identify and validate biological markers for disease diagnosis, prognosis, or treatment response.
- Analyze patient samples and monitor biological responses during clinical trials.